Variable reactive hyperemia in normotensive strains of rat

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Variable reactive hyperemia in normotensive strains of rat

Previous studies from our laboratory report variation in nitric oxide (NO)-dependent arterial pressure within the same strain of normotensive Sprague-Dawley rat dependent upon the commercial vendor supplying the rats. Clinical assessment of endothelial NO activity and endothelial function in general has used postocclusion, flow-mediated dilation (FMD). Therefore, this study was conducted to det...

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Histamine H3 receptors modulate reactive hyperemia in rat gut.

Reactive hyperemia (RH) is an abrupt blood flow increase following release from mechanical occlusion of an artery, with restoration of intra-arterial pressure. The mechanism of this postocclusion increase in blood flow in the gut is multifactorial. Relaxation of intestinal resistance vessels, observed during RH, may involve myogenic, metabolic, hormonal and neurogenic factors. Evidence exists t...

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Comparison Of Cardiovascular Characteristics In Normotensive And Hypertensive Rat Strains.

BACKGROUND Hypertensive rats serve as valuable tools for studies of dysregulations in cardiovascular functions before and during pathological elevation of blood pressure. They exhibit many defects in structure and function of heart and vessels which are often related to severity of hypertension. OBJECTIVE The relationship of blood pressure level and manifestation of aberrations in selected ca...

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Reactive hyperemia revisited.

To the Editor: We read with great interest Dr Huang’s study, published in Arteriosclerosis, Thrombosis, and Vascular Biology.1 We are in total agreement with the authors about the clinical relevance in the perioperative setting of the hyperemic flow velocity, measured by brachial artery Doppler ultrasound. Dr Huang suggests that reactive hyperemia increases the accuracy of the noninvasive vascu...

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Since the description of the classical cardiovascular risk factors by the Framingham group some 50 years ago,1 more recent efforts have explored the utility of biomarkers to further refine risk stratification. Although vascular imaging and biochemical markers have shown considerable promise,2 assessment of vascular function has particular appeal. Endothelial dysfunction is an attendant feature ...

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ژورنال

عنوان ژورنال: Physiological Reports

سال: 2014

ISSN: 2051-817X

DOI: 10.14814/phy2.12052